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BKN-1

BKN-1 is a bifunctional, far-red emissive probe for tracking mitochondrial G-quadruplex (mtG4) formation in live cells. Its mtG4 binding induces mitochondrial dysfunction, including mtDNA loss, reduced ATP, and elevated ROS, leading to anti-tumor effects through apoptosis and autophagy in cellular models.

Product Specifications

CAS Number

1607831-82-2

Field of Research

Cell Biology

Smiles

CC1 (C) C2=C ([N+] (C) =C1C=CC=3C=C4C (=CC3) N (CC) C=5C4=CC=CC5) C=CC=6C2=CC=CC6.[I-]

Molecular Formula

C31H29IN2

Molecular Weight

556.48

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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