CCR8 antagonist 3
CCR8 antagonist 3 (compound 2) is a potent and metabolically stable small molecule CCR8 inhibitor with an IC50 of 62 nM. This tool compound enables research into CCR8-mediated biology, applicable for in vitro binding assays and in vivo studies targeting Treg function within the tumor microenvironment.
Product Specifications
CAS Number
912463-57-1
Field of Research
Immunology & Inflammation, Immunology & Inflammation; Pharmacology & Drug Discovery, Infectious Disease & Virology, Pharmacology & Drug Discovery
Smiles
C (=O) (N1CCC2 (CC1) CCN (CC3=C (OC4=C (OC) C=CC=C4) C=CC=C3) CC2) C=5C (=O) NC=CC5
Molecular Formula
C29H33N3O4
Molecular Weight
487.59
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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