CD 10899
CD 10899 is a hydroxylated metabolite of Volasertib and a potent, ATP-competitive inhibitor of Polo-like kinase 1 (PLK1) with an IC50 of 6 nM. This active metabolite is utilized in cancer research for investigating PLK1 signaling in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
1331770-20-7
Field of Research
Cell Biology
Smiles
C (C) (C) N1C=2C (N (C) C (=O) C1 (CC) O) =CN=C (NC3=C (OC) C=C (C (N[C@H]4CC[C@@H] (CC4) N5CCN (CC6CC6) CC5) =O) C=C3) N2
Molecular Formula
C34H50N8O4
Molecular Weight
634.81
Storage Conditions
-20°C
Notes
For research use only.
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