CDK2-IN-23
CDK2-IN-23 (Compound 17) is a highly selective and potent CDK2 inhibitor (IC50 = 0.29 nM) . It exhibits pharmacodynamic activity in CCNE1-amplified mouse tumor models, supporting its use in cancer research for studying CDK2-dependent mechanisms in vitro and in vivo.
Product Specifications
CAS Number
2488073-20-5
Field of Research
Cell Biology, Epigenetics & Chromatin
Smiles
C (F) (F) (F) C=1C (=NC (NC2CCN (S (=O) (=O) C3CC3) CC2) =NC1) C4=CN (CC (C) (C) O) N=C4
Molecular Formula
C20H27F3N6O3S
Molecular Weight
488.53
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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