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CDK2-IN-23

CDK2-IN-23 (Compound 17) is a highly selective and potent CDK2 inhibitor (IC50 = 0.29 nM) . It exhibits pharmacodynamic activity in CCNE1-amplified mouse tumor models, supporting its use in cancer research for studying CDK2-dependent mechanisms in vitro and in vivo.

Product Specifications

CAS Number

2488073-20-5

Field of Research

Cell Biology, Epigenetics & Chromatin

Smiles

C (F) (F) (F) C=1C (=NC (NC2CCN (S (=O) (=O) C3CC3) CC2) =NC1) C4=CN (CC (C) (C) O) N=C4

Molecular Formula

C20H27F3N6O3S

Molecular Weight

488.53

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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