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CDK2-IN-27

CDK2-IN-27 is a potent and selective CDK2 inhibitor, demonstrating sub-10 nM IC50 against CDK2/cyclin E1 and >10-20 nM against CDK2/cyclin B1. This compound is a valuable chemical probe for studying cell cycle regulation, DNA damage response, and oncology research in both cellular and biochemical assays.

Product Specifications

CAS Number

2927473-94-5

Field of Research

Cell Biology, Epigenetics & Chromatin

Smiles

N (C=1C=C (NN1) [C@@H]2C[C@H] (OC (NC3 (C) CC3) =O) CC2) C=4C=NC (C#N) =CN4

Molecular Formula

C18H21N7O2

Molecular Weight

367.41

Storage Conditions

-20°C

Notes

For research use only.

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