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CGAS-IN-2

CGAS-IN-2 (compound 109) is a highly potent and selective inhibitor of human cGAS, demonstrating an IC50 of 15.12 nM. This tool compound is widely used in biochemical and cellular assays to investigate the cGAS-STING signaling pathway in autoimmune diseases, cancer immunology, and viral infection research.

Product Specifications

CAS Number

2765273-11-6

Field of Research

Immunology & Inflammation, Infectious Disease & Virology

Smiles

C[C@H]1C=2C=3C (NC2C[C@@H] (C) N1C (COC) =O) =C (Cl) C (Cl) =CC3

Molecular Formula

C16H18Cl2N2O2

Molecular Weight

341.23

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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