CMX990
CMX990 is a potent small molecule inhibitor of the SARS-CoV-2 3CL protease, demonstrating antiviral activity with EC90 values of 9.6 nM in human bronchial epithelial cells and 101 nM in HeLa-ACE2 cells. It features favorable ADME/PK properties, supporting its utility for in vitro antiviral mechanism studies and preclinical in vivo research on coronavirus infections.
Product Specifications
CAS Number
2882934-64-5
Field of Research
Infectious Disease & Virology
Smiles
C (N[C@@H] (C[C@H]1C (=O) NCC1) C (COC (F) (F) F) =O) (=O) [C@@H]2CC3 (CN2C ([C@@H] (CC (C) C) O) =O) CC3
Molecular Formula
C22H32F3N3O6
Molecular Weight
491.50
Storage Conditions
-20°C
Notes
For research use only.
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