CSF1R-IN-20
CSF1R-IN-20 (7a) is a potent small molecule inhibitor of CSF-1R, demonstrating an IC50 of 467 nM and effectively blocking its auto-phosphorylation. This compound is a valuable research tool for studying macrophage biology and tumor microenvironment in both cellular and animal models of cancer and inflammatory diseases.
Product Specifications
CAS Number
2935479-57-3
Field of Research
Signal Transduction
Smiles
C (NC1=CC (NC (=O) C2=NOC (C) =C2) =C (C) C=C1) (=O) C=3C=C (C=C (C (F) (F) F) C3) N4CCN (C) CC4
Molecular Formula
C25H26F3N5O3
Molecular Weight
501.5
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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