CTSL/CAPN1-IN-2
CTSL/CAPN1-IN-2 (Compound 14b) is a dual, orally bioavailable inhibitor of cathepsin L (CTSL) and calpain-1 (CAPN1) with IC50 values of 6.88 nM and 347.6 nM, respectively. It exhibits anti-inflammatory activity, favorable pharmacokinetics, and broad-spectrum antiviral effects against coronaviruses by blocking viral cell entry, supporting research in virology and immunology.
Product Specifications
CAS Number
2410075-64-6
Field of Research
Infectious Disease & Virology, Neuroscience, Protein Biochemistry
Smiles
C (N[C@@H] (CC1CCCCC1) C (N[C@@H] (C[C@H]2C (=O) NCCC2) C (C (NCC3=CC=CC=C3) =O) =O) =O) (=O) C4=CC=5C (O4) =CC=CC5
Molecular Formula
C34H40N4O6
Molecular Weight
600.7
Storage Conditions
-20°C
Notes
For research use only.
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