CVN766
CVN766 is a brain-penetrant, selective orexin 1 receptor (OX1R) antagonist with an IC50 of 8 nM, showing >1000-fold selectivity over OX2R. This tool compound is used in research for investigating the role of the orexin system in neuropsychiatric disorders, including in vitro binding assays and in vivo models relevant to schizophrenia.
Product Specifications
CAS Number
1803557-42-7
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Smiles
C (N[C@@H]1[C@@H] (NC=2C (CC) =NC (C (F) (F) F) =CN2) CCC1) (=O) C3=C (C=CC=N3) N4N=CC=N4
Molecular Formula
C20H21F3N8O
Molecular Weight
446.43
Storage Conditions
-20°C
Notes
For research use only.
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