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CW0134

CW0134 (Compound 12) is an exportin 1 (XPO1) modulator that interferes with chromatin association, leading to the inhibition of NFAT transcription factors and suppression of T cell activation. This small molecule is a valuable research tool for studying immune regulation and nuclear export in both cellular and animal models of inflammation and autoimmunity.

Product Specifications

CAS Number

1076235-18-1

Field of Research

Pharmacology & Drug Discovery

Smiles

N (N1C (=O) C (C) =CC1=O) C=2N=C (Cl) C (C (F) (F) F) =CC2

Molecular Formula

C11H7ClF3N3O2

Molecular Weight

305.64

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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