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CZL80

CZL80 is a potent, brain-penetrant caspase-1 inhibitor (IC50 = 0.01 μM) used to study neuroinflammation. It reduces neuronal excitability, suppresses febrile seizures in vivo at 7.5 mg/kg i.v., and mitigates long-term deficits in stroke models, making it a key tool for seizure and stroke pathology research.

Product Specifications

CAS Number

313482-91-6

Product Name Alternative

CZL 80, CZL-80

Field of Research

Cell Biology, Protein Biochemistry

Purity

99.48% (May vary between batches)

Solubility

DMSO:≥ 160 mg/mL

Smiles

O=C (O) C=1C=CC=C (C1) NC (=O) C=2C=CC=C (C2) NC (=O) C=3SC=CC3

Molecular Formula

C19H14N2O4S

Molecular Weight

366.39

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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