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DB18

DB18 is a potent and selective small molecule inhibitor of CDC2-like kinases (CLKs), demonstrating IC50 values of 10-30 nM against CLK1, CLK2, and CLK4. It exhibits anti-tumor activity and is a valuable chemical probe for studying CLK function in cancer biology, splicing regulation, and in vitro cellular assays.

Product Specifications

CAS Number

2587177-94-2

Field of Research

Cell Biology

Smiles

O (CC1=CN (N=N1) C2=C (N (=O) =O) C=C (C) C=C2) C=3C4=C (C=NC (NC5=CC (Cl) =CC=C5) =N4) C=CC3

Molecular Formula

C24H18ClN7O3

Molecular Weight

487.9

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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