DB18
DB18 is a potent and selective small molecule inhibitor of CDC2-like kinases (CLKs), demonstrating IC50 values of 10-30 nM against CLK1, CLK2, and CLK4. It exhibits anti-tumor activity and is a valuable chemical probe for studying CLK function in cancer biology, splicing regulation, and in vitro cellular assays.
Product Specifications
CAS Number
2587177-94-2
Field of Research
Cell Biology
Smiles
O (CC1=CN (N=N1) C2=C (N (=O) =O) C=C (C) C=C2) C=3C4=C (C=NC (NC5=CC (Cl) =CC=C5) =N4) C=CC3
Molecular Formula
C24H18ClN7O3
Molecular Weight
487.9
Storage Conditions
-20°C
Notes
For research use only.
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