DHODH-IN-25
DHODH-IN-25 (Compound 25) is a potent, orally bioavailable dihydroorotate dehydrogenase (DHODH) inhibitor with an IC50 of 5.4 nM against the human enzyme. It is a valuable research tool for studying acute myeloid leukemia (AML), with utility in both in vitro cellular assays and in vivo preclinical models.
Product Specifications
CAS Number
2619531-95-0
Field of Research
Cell Biology, Metabolism Research, Molecular Biology
Smiles
O ([C@H] (C (F) (F) F) C) C1=C (C (NC2=C (Cl) C=CC=C2F) =O) C=C (F) C (NC (=O) N3C (CO) CCC3=O) =C1
Molecular Formula
C22H19ClF5N3O5
Molecular Weight
535.85
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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