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E3 Ligase Ligand-linker Conjugate 50

E3 Ligase Ligand-linker Conjugate 50 is a VHL-recruiting (S, R, S) -AHPC derivative linked to a chemical spacer, serving as a key intermediate for constructing PROTAC degraders. This tool compound is widely used in both cellular and in vivo studies to investigate targeted protein degradation.

Product Specifications

CAS Number

2918813-56-4

Field of Research

Molecular Biology, Pharmacology & Drug Discovery

Smiles

C ([C@@H] (NC (=O) C1CCN (C (OC (C) (C) C) =O) CC1) [C@@] (C) (C) C) (=O) N2[C@H] (C (NCC3=CC=C (C=C3) C4=C (C) N=CS4) =O) C[C@@H] (O) C2

Molecular Formula

C33H47N5O6S

Molecular Weight

641.82

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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