E3 Ligase Ligand-linker Conjugate 58
E3 Ligase Ligand-linker Conjugate 58 is a thalidomide-based Cereblon (CRBN) recruiting moiety attached to a linker. It is a key intermediate for constructing PROTAC degraders, which are widely used in chemical biology and drug discovery research for targeted protein degradation in both cellular and in vivo studies.
Product Specifications
CAS Number
2229725-27-1
Field of Research
Molecular Biology, Pharmacology & Drug Discovery
Smiles
O=C1N (C (=O) C=2C1=CC (=CC2) N3CCN (CC4CCN (C (OC (C) (C) C) =O) CC4) CC3) C5C (=O) NC (=O) CC5
Molecular Formula
C28H37N5O6
Molecular Weight
539.62
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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