Edonentan hydrate
Edonentan (BMS 207940) hydrate is a highly potent and selective endothelin A (ETA) receptor antagonist with a K i of 10 pM. It demonstrates 100% oral bioavailability in rats, making it a valuable tool for investigating the role of ET-1 in cardiovascular and renal disease models in both in vitro and in vivo studies.
Product Specifications
CAS Number
264609-13-4
Field of Research
Pharmacology & Drug Discovery
Smiles
C (N (C (CC (C) (C) C) =O) C) C1=C (C=CC (=C1) C2=NC=CO2) C3=C (S (NC=4C (C) =C (C) ON4) (=O) =O) C=CC=C3.O
Molecular Formula
C28H34N4O6S
Molecular Weight
554.66
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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