EGFR T790M/L858R-IN-5
EGFR T790M/L858R-IN-5 (Example 52) is a highly effective small molecule inhibitor, showing 92.9% inhibition of the EGFR T790M/L858R mutant at 50 nM. This compound is a valuable research tool for studying resistant non-small cell lung cancer (NSCLC) in both biochemical and cellular assays.
Product Specifications
CAS Number
3032760-70-3
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
CN1C=C (C=2C1=CC=CC2) C3=NC (NC4=C (OC) C=C (NCCN (C) C) C (NC=5C=CN=CN5) =C4) =NC=C3
Molecular Formula
C28H31N9O
Molecular Weight
509.61
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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