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EGFR T790M/L858R-IN-6

EGFR T790M/L858R-IN-6 (compound 53) is a potent pyrimidine-based inhibitor of the EGFR T790M/L858R mutant, showing 90.88% enzyme inhibition at 0.05 μM. It is a valuable research tool for studying resistant non-small cell lung cancer (NSCLC) in biochemical and cellular assays.

Product Specifications

CAS Number

3032760-71-4

Field of Research

Cardiovascular Research, Cell Biology, Signal Transduction

Smiles

CN1C=C (C=2C1=CC=CC2) C3=NC (NC4=C (OC) C=C (NCCO) C (NC5=CC=CC=N5) =C4) =NC=C3

Molecular Formula

C27H27N7O2

Molecular Weight

481.55

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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