EGFR T790M/L858R-IN-6
EGFR T790M/L858R-IN-6 (compound 53) is a potent pyrimidine-based inhibitor of the EGFR T790M/L858R mutant, showing 90.88% enzyme inhibition at 0.05 μM. It is a valuable research tool for studying resistant non-small cell lung cancer (NSCLC) in biochemical and cellular assays.
Product Specifications
CAS Number
3032760-71-4
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
CN1C=C (C=2C1=CC=CC2) C3=NC (NC4=C (OC) C=C (NCCO) C (NC5=CC=CC=N5) =C4) =NC=C3
Molecular Formula
C27H27N7O2
Molecular Weight
481.55
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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