EGFR/HER2-IN-12
EGFR/HER2-IN-12 (14b) is a dual EGFR/HER2 inhibitor, showing 81% and 51% inhibition at 10 μM, respectively. It displays low cytotoxicity in A431 and MDA-MB-361 cell lines, making it a useful research tool for studying EGFR/HER2-driven cancers in vitro.
Product Specifications
CAS Number
2237230-21-4
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
N (C1=C2C (SC (=C2) C3=CC=C (N (=O) =O) C=C3) =NC=N1) C4=CC (Cl) =C (OC5=CC (C) =CC=C5) C=C4
Molecular Formula
C25H17ClN4O3S
Molecular Weight
488.95
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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