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EGFR/HER2-IN-12

EGFR/HER2-IN-12 (14b) is a dual EGFR/HER2 inhibitor, showing 81% and 51% inhibition at 10 μM, respectively. It displays low cytotoxicity in A431 and MDA-MB-361 cell lines, making it a useful research tool for studying EGFR/HER2-driven cancers in vitro.

Product Specifications

CAS Number

2237230-21-4

Field of Research

Cardiovascular Research, Cell Biology, Signal Transduction

Smiles

N (C1=C2C (SC (=C2) C3=CC=C (N (=O) =O) C=C3) =NC=N1) C4=CC (Cl) =C (OC5=CC (C) =CC=C5) C=C4

Molecular Formula

C25H17ClN4O3S

Molecular Weight

488.95

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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