EGFR-IN-101
EGFR-IN-101 (I-10) is a 2-phenylamino pyrimidine-based EGFR inhibitor, demonstrating potent activity against resistant mutants including L858R/T790M/C797S. This compound is a valuable research tool for investigating non-small cell lung cancer (NSCLC), applicable in both in vitro enzymatic assays and cellular studies using models like Ba/F3-EGFR mutant cells.
Product Specifications
CAS Number
2982583-44-6
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
C (N[C@H] (CO) C) C=1C (=NN (C1) C2=NC (NC3=C (OC) C=C (C (C) =C3) N4CCC (CC4) N5CCN (C) CC5) =NC=C2) C6=CC=CC=C6
Molecular Formula
C35H47N9O2
Molecular Weight
625.81
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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