EGFR-IN-109
EGFR-IN-109 is a potent and selective EGFR inhibitor with IC50 values of 25.8 nM (WT) and 182.3 nM (T790M mutant) . It induces G2/M phase cell cycle arrest and apoptosis in cancer cells, making it a valuable chemical probe for oncology research in both cellular and biochemical assays.
Product Specifications
CAS Number
3019971-97-9
Field of Research
Cardiovascular Research, Cell Biology, Protein Biochemistry, Signal Transduction
Smiles
O=C1C=2C3=C (SC2NC (CNN) =N1) CC (C) CC3
Molecular Formula
C12H16N4OS
Molecular Weight
264.35
Storage Conditions
-20°C
Notes
For research use only.
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