EGFR-IN-97
EGFR-IN-97 is a potent EGFR inhibitor effective against Ba/F3 cells harboring L858R/T790M/C797S or Del19/T790M/C797S mutations, with IC50 values of approximately 0.4 μM. It also induces apoptosis in NCI-H1975-EGFR L858R/T790M/C797S cells at 0.8 μM. This compound is a valuable research tool for studying resistant non-small cell lung cancer (NSCLC) in vitro.
Product Specifications
CAS Number
3020681-05-1
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
[C@@H] (C (NC1=CC=C (NC2=NC (N) =NC=C2) C=C1) =O) (N3CC=4C (C3=O) =CC=C (C4) C5=CC=C (C=C5) N6CCN (C) CC6) C7=CC=CC=C7
Molecular Formula
C37H36N8O2
Molecular Weight
624.73
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
034234 200 µL
CRLF1, ID (CRLF1, Cytokine receptor-like factor 1, Cytokine-like factor 1, ZcytoR5)
Sign In for Pricing
View Details 
495220 100 µL
UQCRC1 (Cytochrome b-c1 Complex Subunit 1, Mitochondrial, Ubiquinol-Cytochrome c Reductase Core Protein I)
Sign In for Pricing
View Details 38138066 1.0 µg DNA
PTP4A3 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
Sign In for Pricing
View Details 132552-APC 100 µL
RHEBL1 (GTPase RhebL1, Ras Homolog Enriched in Brain Like-1 c, Ras Homolog Enriched in Brain-like Protein 1, Rheb2, FLJ25797, MGC34869) (APC)
Sign In for Pricing
View Details