Emavusertib hydrochloride
Emavusertib (CA-4948) hydrochloride is an orally bioavailable, potent dual inhibitor of IRAK4 and FLT3 kinases, with an IC50 of 57 nM against IRAK4. It is used in preclinical research for studying hematological malignancies and solid tumors, demonstrating antitumor activity in both cellular assays and in vivo models.
Product Specifications
CAS Number
2376399-42-5
Field of Research
Cardiovascular Research, Cell Biology, Immunology & Inflammation, Signal Transduction
Smiles
N (C (=O) C=1N=C (OC1) C=2C=C (C) N=CC2) C3=C (N=C4C (=C3) OC (=N4) N5CCOCC5) N6CC[C@@H] (O) C6.Cl
Molecular Formula
C24H26ClN7O5
Molecular Weight
527.96
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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