EP3 antagonist 6
Compound 5 is a potent, selective, and orally bioavailable EP3 receptor antagonist with a 1.9 nM IC50. It is a valuable research tool for studying prostaglandin E2 signaling in models of preterm labor, as demonstrated by its inhibition of PGE2-induced uterine contractions in pregnant rats.
Product Specifications
CAS Number
499149-94-9
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery
Smiles
C (N[C@H] (CC (C) C) C1=CC (C) =CC (C) =C1) (=O) C2=C (CCC (O) =O) C=CC (COC3=C (C) C=CC=C3) =C2
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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