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EP3 antagonist 6

Compound 5 is a potent, selective, and orally bioavailable EP3 receptor antagonist with a 1.9 nM IC50. It is a valuable research tool for studying prostaglandin E2 signaling in models of preterm labor, as demonstrated by its inhibition of PGE2-induced uterine contractions in pregnant rats.

Product Specifications

CAS Number

499149-94-9

Field of Research

Immunology & Inflammation, Pharmacology & Drug Discovery

Smiles

C (N[C@H] (CC (C) C) C1=CC (C) =CC (C) =C1) (=O) C2=C (CCC (O) =O) C=CC (COC3=C (C) C=CC=C3) =C2

Storage Conditions

-20°C

Notes

For research use only.

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