F44-A13
F44-A13 is a potent and selective oral FXR antagonist (IC50 = 1.1 μM) that modulates lipid metabolism. It upregulates CYP7A1, leading to reduced cholesterol, triglycerides, and LDL-C in mouse models, making it a valuable research tool for studying dyslipidemia and related metabolic disorders.
Product Specifications
CAS Number
1338190-14-9
Field of Research
Metabolism Research, Molecular Biology
Smiles
C (N (CC1CC1) C (NC (C) (C) C) =O) C2=C (OS (=O) (=O) C3=CC=C (NC (C) =O) C=C3) C=C (N (CC) CC) C=C2
Molecular Formula
C28H40N4O5S
Molecular Weight
544.71
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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