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GNE-555

GNE-555 is a potent, selective, and metabolically stable mTOR inhibitor (Ki=1.5 nM) with demonstrated oral bioavailability. It exhibits antiproliferative activity in vitro against cancer cell lines such as PC3 and MCF-7, supporting its utility in oncology research for both in vitro and in vivo experimental applications.

Product Specifications

CAS Number

1428902-71-9

Field of Research

Signal Transduction

Smiles

C[C@@H]1N (C2=C3C ([C@@]4 (N ([C@] (C3) (CC4) [H]) C5COC5) [H]) =NC (=N2) C6=CC=C (NC (NCC) =O) C=C6) CCOC1

Molecular Formula

C26H34N6O3

Molecular Weight

478.59

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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