GNE-555
GNE-555 is a potent, selective, and metabolically stable mTOR inhibitor (Ki=1.5 nM) with demonstrated oral bioavailability. It exhibits antiproliferative activity in vitro against cancer cell lines such as PC3 and MCF-7, supporting its utility in oncology research for both in vitro and in vivo experimental applications.
Product Specifications
CAS Number
1428902-71-9
Field of Research
Signal Transduction
Smiles
C[C@@H]1N (C2=C3C ([C@@]4 (N ([C@] (C3) (CC4) [H]) C5COC5) [H]) =NC (=N2) C6=CC=C (NC (NCC) =O) C=C6) CCOC1
Molecular Formula
C26H34N6O3
Molecular Weight
478.59
Storage Conditions
-20°C
Notes
For research use only.
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