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HDAC6-IN-34

HDAC6-IN-34 (compound 21) is a potent and selective HDAC6 inhibitor (IC50 = 18 nM) that increases tubulin acetylation in lymphoma cells and reduces TNF-α in macrophages. It has demonstrated significant oral anti-arthritic activity in rat models, supporting its use in oncology and inflammation research.

Product Specifications

CAS Number

1432508-73-0

Field of Research

Epigenetics & Chromatin, Molecular Biology

Smiles

C (N1C2=C (C (C (F) (F) F) =N1) C (=O) CC (C) (C) C2) C3=CC=C (C (NO) =O) C=C3

Molecular Formula

C18H18F3N3O3

Molecular Weight

381.35

Storage Conditions

-20°C

Notes

For research use only.

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