HDAC6-IN-34
HDAC6-IN-34 (compound 21) is a potent and selective HDAC6 inhibitor (IC50 = 18 nM) that increases tubulin acetylation in lymphoma cells and reduces TNF-α in macrophages. It has demonstrated significant oral anti-arthritic activity in rat models, supporting its use in oncology and inflammation research.
Product Specifications
CAS Number
1432508-73-0
Field of Research
Epigenetics & Chromatin, Molecular Biology
Smiles
C (N1C2=C (C (C (F) (F) F) =N1) C (=O) CC (C) (C) C2) C3=CC=C (C (NO) =O) C=C3
Molecular Formula
C18H18F3N3O3
Molecular Weight
381.35
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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