HG-7-86-01
HG-7-86-01 is a type II, potent, and selective tyrosine kinase inhibitor designed to target the drug-resistant Bcr-Abl T315I mutant in chronic myeloid leukemia (CML) . It demonstrates robust antiproliferative effects in vitro and has shown efficacy in preclinical CML models, supporting its use as a valuable research tool in oncology and kinase inhibitor development.
Product Specifications
CAS Number
1258391-14-8
Field of Research
Cardiovascular Research, Signal Transduction
Purity
99.07% (May vary between batches)
Solubility
DMSO:2 mg/mL (3.56 mM)
Smiles
O=C (NC=1C=C (C=C (C1) C (F) (F) F) N2C=NC (=C2) C) C3=CC=CC (=C3) C4=NC=5SC (=NC5C=C4) NC (=O) C6CC6
Molecular Formula
C28H21F3N6O2S
Molecular Weight
562.57
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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