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HG-7-86-01

HG-7-86-01 is a type II, potent, and selective tyrosine kinase inhibitor designed to target the drug-resistant Bcr-Abl T315I mutant in chronic myeloid leukemia (CML) . It demonstrates robust antiproliferative effects in vitro and has shown efficacy in preclinical CML models, supporting its use as a valuable research tool in oncology and kinase inhibitor development.

Product Specifications

CAS Number

1258391-14-8

Field of Research

Cardiovascular Research, Signal Transduction

Purity

99.07% (May vary between batches)

Solubility

DMSO:2 mg/mL (3.56 mM)

Smiles

O=C (NC=1C=C (C=C (C1) C (F) (F) F) N2C=NC (=C2) C) C3=CC=CC (=C3) C4=NC=5SC (=NC5C=C4) NC (=O) C6CC6

Molecular Formula

C28H21F3N6O2S

Molecular Weight

562.57

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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