HSD17B13-IN-17
HSD17B13-IN-17 (compound 9) is a potent inhibitor of hydroxysteroid 17β-dehydrogenase 13, showing IC50 values <0.1 μM and <1 μM against estradiol and Leukotriene B3, respectively. It is a key research tool for investigating the role of HSD17B13 in nonalcoholic fatty liver disease (NAFLD) and steatohepatitis (NASH) in both cellular and animal models.
Product Specifications
CAS Number
2758802-10-5
Field of Research
Metabolism Research
Smiles
C (NCCC1=C (F) C=CC=C1) (=O) C2=C (NC (=O) C3=CC (Cl) =C (O) C=C3) C=CS2
Molecular Formula
C20H16ClFN2O3S
Molecular Weight
418.87
Storage Conditions
-20°C
Notes
For research use only.
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