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HSD17B13-IN-28

HSD17B13-IN-28 (compound 47) is a potent small-molecule inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), exhibiting an IC50 below 0.1 μM. This inhibitor is a valuable research tool for investigating the role of HSD17B13 in liver diseases, particularly in studies of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) using in vitro and in vivo models.

Product Specifications

CAS Number

2770246-42-7

Field of Research

Metabolism Research

Smiles

N (C (=O) C1=CC (Cl) =C (O) C (Cl) =C1) C2=C3C (N=CN ([C@H] (C) C4=CC (F) =CC=C4) C3=O) =CC=C2

Molecular Formula

C23H16Cl2FN3O3

Molecular Weight

472.3

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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