HSD17B13-IN-35
HSD17B13-IN-35 (compound 76) is a potent small-molecule inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 < 0.1 μM. It serves as a key research tool for investigating the role of HSD17B13 in liver lipid metabolism and is relevant for studies on nonalcoholic fatty liver disease (NAFLD) and steatohepatitis (NASH) in both cellular and animal models.
Product Specifications
CAS Number
2770246-69-8
Field of Research
Metabolism Research
Smiles
N (C (=O) C1=CC (Cl) =C (O) C (Cl) =C1) C2=C3C (N=CN (CC4=NN (C=C4) C5=C (F) C=CC=C5) C3=O) =CC=C2
Molecular Formula
C25H16Cl2FN5O3
Molecular Weight
524.33
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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