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HSD17B13-IN-45

HSD17B13-IN-45 (Compound 195) is a potent small molecule inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), demonstrating an IC50 < 0.1 μM against estradiol. This compound serves as a valuable research tool for investigating the role of HSD17B13 in liver diseases such as NAFLD/NASH and metabolic disorders in both cellular and animal models.

Product Specifications

CAS Number

2912452-50-5

Field of Research

Metabolism Research

Smiles

N (S (=O) (=O) C=1N=C (C#CC2=C (Cl) C=CC=C2) SC1) C3=C (OC) C=C (C (O) =O) C=C3

Molecular Formula

C19H13ClN2O5S2

Molecular Weight

448.9

Storage Conditions

-20°C

Notes

For research use only.

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