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HSD17B13-IN-48

HSD17B13-IN-48 (Compound 12) is a potent small molecule inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 ≤ 0.1 μM against estradiol. It is a valuable research tool for investigating the role of HSD17B13 in liver diseases such as NAFLD, NASH, and DILI, as well as in metabolic and cardiovascular research contexts.

Product Specifications

CAS Number

2770246-12-1

Field of Research

Metabolism Research

Smiles

N (C (=O) C1=CC (Cl) =C (O) C (Cl) =C1) C2=C3C (N=CN ([C@@H] (C) C4=CC (F) =CC=C4) C3=O) =CC=C2

Molecular Formula

C23H16Cl2FN3O3

Molecular Weight

472.30

Storage Conditions

-20°C

Notes

For research use only.

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