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HSD17B13-IN-49

HSD17B13-IN-49 (Compound 81) is a potent small-molecule inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), exhibiting an IC50 ≤ 0.1 μM against estradiol. It is a valuable research tool for investigating the role of HSD17B13 in liver diseases such as NAFLD, NASH, and DILI, both in vitro and in preclinical models.

Product Specifications

CAS Number

2770246-74-5

Field of Research

Metabolism Research

Smiles

N (C (=O) C1=CC (Cl) =C (O) C (Cl) =C1) C2=C3C (N=CN (CC4=C (OC (F) (F) F) C=CC=C4) C3=O) =C (Cl) C=C2

Molecular Formula

C23H13Cl3F3N3O4

Molecular Weight

558.72

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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