HSD17B13-IN-56
HSD17B13-IN-56 (Compound 89) is a potent small molecule inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), demonstrating an IC50 of ≤0.1 μM against estradiol. It is a valuable research tool for investigating the role of HSD17B13 in liver diseases such as NAFLD, NASH, and DILI, as well as in metabolic and cardiovascular disorders, in both in vitro and in vivo studies.
Product Specifications
CAS Number
2770246-82-5
Field of Research
Metabolism Research
Smiles
N (C (=O) C1=CC (Cl) =C (O) C (Cl) =C1) C2=C3C (N=C (C) N (CC4=C (OC (F) (F) F) C=CC=C4) C3=O) =C (C) C=C2
Molecular Formula
C25H18Cl2F3N3O4
Molecular Weight
552.33
Storage Conditions
-20°C
Notes
For research use only.
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