HSD17B13-IN-61
HSD17B13-IN-61 (Compound 132) is a potent small-molecule inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 ≤ 0.1 μM against estradiol. It is a valuable research tool for investigating the role of HSD17B13 in liver diseases such as NAFLD/NASH, metabolic disorders, and drug-induced liver injury (DILI) in both in vitro and in vivo models.
Product Specifications
CAS Number
2770247-26-0
Field of Research
Metabolism Research
Smiles
N (C (=O) C1=CC (Cl) =C (O) C (Cl) =C1) C2=C3C (N=CN (CC4=C (OC (F) (F) F) C=CC=C4) C3=O) =C (F) C=C2
Molecular Formula
C23H13Cl2F4N3O4
Molecular Weight
542.27
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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