HSD17B13-IN-66
HSD17B13-IN-66 (Compound 146) is a potent inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), exhibiting an IC50 of ≤0.1 μM against estradiol. It is a valuable research tool for investigating liver diseases such as NAFLD, NASH, and DILI, as well as related metabolic and cardiovascular disorders, in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
2770247-37-3
Field of Research
Metabolism Research
Smiles
N (C (=O) C1=CC (Cl) =C (O) C (Cl) =C1) C2=C3C (N=C (C) N (CC4=C (C (F) (F) F) C=CC=N4) C3=O) =C (C) C=C2
Molecular Formula
C24H17Cl2F3N4O3
Molecular Weight
537.32
Storage Conditions
-20°C
Notes
For research use only.
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