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HSD17B13-IN-71

HSD17B13-IN-71 (Compound 149) is a potent small-molecule inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), demonstrating an IC50 of ≤0.1 μM against estradiol. It is a valuable research tool for investigating the role of HSD17B13 in liver and metabolic diseases, including NAFLD, NASH, and drug-induced liver injury, in both in vitro and in vivo models.

Product Specifications

CAS Number

2770247-40-8

Field of Research

Metabolism Research

Smiles

N (C (=O) C1=CC (Cl) =C (O) C (Cl) =C1) C2=C3C (N=C (C (F) F) N (CC4=C (OC (F) (F) F) C=CC=C4) C3=O) =C (C) C=C2

Molecular Formula

C25H16Cl2F5N3O4

Molecular Weight

588.31

Storage Conditions

-20°C

Notes

For research use only.

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