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HSD17B13-IN-75

HSD17B13-IN-75 (Compound 21) is a potent small molecule inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), exhibiting an IC50 ≤ 0.1 μM against estradiol. It is a research tool for investigating liver pathologies such as NAFLD, NASH, and DILI in both cellular and animal model studies.

Product Specifications

CAS Number

2770246-20-1

Field of Research

Metabolism Research

Smiles

O=C1N (C2 (CC2) C3=C (F) C=CC=C3) C=NC=4C1=C (NC (=O) C5=CC (Cl) =C (O) C (Cl) =C5) C=CC4

Molecular Formula

C24H16Cl2FN3O3

Molecular Weight

484.31

Storage Conditions

-20°C

Notes

For research use only.

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