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HSD17B13-IN-8

HSD17B13-IN-8 (1) is a potent small-molecule inhibitor of 17β-hydroxysteroid dehydrogenase 13 (HSD17B13), demonstrating IC50 values below 0.1 μM for estradiol and under 1 μM for LTB3. It is a valuable research tool for investigating the role of HSD17B13 in metabolic liver diseases, including nonalcoholic fatty liver disease (NAFLD), in both cellular and animal models.

Product Specifications

CAS Number

2758802-02-5

Field of Research

Metabolism Research

Smiles

C (NCCC1=C (OC) C=CC=C1) (=O) C2=C (NC (=O) C3=CC (Cl) =C (O) C=C3) C=CS2

Molecular Formula

C21H19ClN2O4S

Molecular Weight

430.9

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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