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HSD17B13-IN-83

HSD17B13-IN-83 (Compound 150) is a potent inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), demonstrating an IC50 of ≤ 0.1 μM against estradiol. It is a valuable research tool for investigating liver pathologies such as NAFLD, NASH, and drug-induced liver injury (DILI) in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

2770247-41-9

Field of Research

Metabolism Research

Smiles

N (C (=O) C1=CC (Cl) =C (O) C (Cl) =N1) C2=C3C (N=C (C) N (CC4=C (OC (F) (F) F) C=CC=C4) C3=O) =C (F) C=C2

Molecular Formula

C23H14Cl2F4N4O4

Molecular Weight

557.28

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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